I've been using the Nomad 16 as my work tote for about a month now and absolutely love it.
The straps are comfortable and just the right length. I haven't had need for the crossbody strap so far, but it also seems to be high quality.
The front zip pocket is perfect for things I need easy access to like my keys, mobile phone, work badge, kleenex, pens, etc. The main compartment is spacious and easily accommodates my water bottle, a small toiletries/make up bag, my wallet, a medium sized notebook, an e-reader, my lunch when I bring it to work, and has room to spare. I don't typically have to bring a laptop back and forth, but do use the laptop pocket for papers and folders, and it works great. I haven't traveled with it yet, but I could also see it working wonderfully as a personal item.
As one would expect from Tom Bihn, the craftsmanship is top notch, and I love that it's sewn in the USA. I chose the black ballistic exterior with Northwest Sky halcyon interior and the light colored interior makes it easy to find anything I'm looking for in any of the pockets. I'm very tempted by a couple of the other colors on offer, and may have to spring for a second, or even third one.