I really like my Synapse, but I want to adore it. The pockets in the Synapse are fantastic if you are just carrying this bag, but they can work against a bag-in-bag packer like me. I'm used to having a larger backpack that I can toss a purse into, and its extra size just swallows the bulky purse up and doesn't bat an eye. With the Synapse, I'm using up vital real estate for the purse that otherwise would have been used for important stuff...like, well, snacks.
I think what would be the Ultimate Fantastic Awesome Solution would be a smaller Dyneema bag, along the lines of a Side Effect but without the added bulk of the waist straps (and here I go again, sorry) or maybe a mini Packing Cube Shoulder Bag or Unclear Quarter Packing Cube. Then I would have a squishable purse-like object that's not taking up too much space on its own, but that would satisfy this need I have to keep a small bag with my wallet and phone in it, one that I could clip a 16" key strap to for an over-the-arm purse, or a long strap to for crossbody carry. Argh!
Maybe I just need to give myself permission to let go of the whole PLO idea. I can hear Obi-Wan Kenobi whispering in my ear, Use the Organizer Pouches, Janine. Just pack the Synapse like a huge purse. I don't know....