My 17" PB lives in an Empire Builder
My beloved 17" PowerBook lives in a Brain Cell tucked into an Empire Builder. I also usually carry a 1TB LaCie Big Disc drive (wrapped up snugly in a Domke wrap), a Snake Charmer with the LaCie cables & cords, a second Snake Charmer (with all of the cables for connecting a USB sound mixer, a video camera, and a TV monitor), rundown sheets for the current show, shot lists for promos & vignettes, my iPod and its cables, and a whole bunch of other stuff.
With the Absolute Strap it is not unbearable to carry and I can't really think of anything negative to say about the experience (other than the controversial EB tipping conversation).
Highly recommended and I'm pretty sure that it will hold everything that you've described with room left over.