Once again I had a week-long business trip and once again my Smart Alec was incredibly perfect. I guess what I'd want in a superduper carryon to accompany it would be somewhere in the neighborhood of this, from Red Oxx: http://tinyurl.com/9ejqk/ ,though of course I'd be happy to see what Tom's working on. If my business travel schedule starts heating up over the next few months (as I suspect it will), I'll be seriously in the market for one of these critters. I agree with what's been said above: ballistic nylon, the kinds of zippers my beloved red Smart Alec has, and as much interior space as possible, since this is a bag that would have to support me for up to a week, and include some bulky stuff I can't leave at home. Oh, and definitely no frame!