My Tom Bihn bags served me very well for my Thailand trip. Let me talk about what I used and then add a photo. I brought two Kits -- one for meds and one for toiletries. I love these because they're not only attractive, but they squish when not full. The 1L size clear organizer cube passed through security in the US, Japan, and Thailand with nary a blink by officials. I brought a variety of zippered pouches and my TB wallet. These were fabulous for everything from organizing papers, sorting Baht from US dollars, storing my passport, housing sticky notes and pens, wireless computer mouse, etc. etc. And because they're all different colors, I could color-code my needs. My Aeronaut was a terrific carry-on, as was my new Ego. I was impressed with how I could store everything I needed for the 20+ hour flights in the Ego and not have to get items out of my Aeronaut (above my seat). The Aeronaut's backpack straps made it easy to traverse 4 airports, two security screenings, and customs/immigration screening (and that's just one direction!).
While I carried my Ego around campus a couple of days, my Ristretto is what I usually carry around each day at work in the US, and I wound up doing the same in Thailand (at a university campus). I can carry what I need, but also I don't carry more than what I need (what I found myself doing with the Ego).
Here's a couple of photos of me carrying my Ristretto at the College of Music, Mahidol University, Thailand: