Just returned from Ecuador and Panama on a 16 day jaunt, I am FED UP with hauling around stuff in hot, humid climates! Nothing like a vacation to prompt me to continually refine my packing lists. I did use a 20" roller bag and my Synapse 25. I am totally sick of the roller, although believe me, standing on security lines for hours is not fun without one. So my next strategy is this: if I have to take a backpack because we do nature travel, then I don't want to haul anything larger than my S25 as my main clothing bag. The introduction of Pilot makes this a very viable option for me, because like most people packing in this forum, the nonclothing GEAR is considerable, and it can all go in there. My question is: Has anyone tetris packed the S25 with clothing only? And what does it look like. I realize sizes may vary.